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Image Search Results


Flow chart of the study. A total of 57 participants were screened, of which 6 were excluded. Of these 51 participants, 3 participants withdrew consent. Of the remaining 48 participants, only the 12 participants that received 20 mg oxycodone were included for the analysis.

Journal: Sensors (Basel, Switzerland)

Article Title: Opioid Detection Using Smartphone-Based Eye-Scanning

doi: 10.3390/s25175467

Figure Lengend Snippet: Flow chart of the study. A total of 57 participants were screened, of which 6 were excluded. Of these 51 participants, 3 participants withdrew consent. Of the remaining 48 participants, only the 12 participants that received 20 mg oxycodone were included for the analysis.

Article Snippet: Thereafter, participants were administered the medicinal product: oxycodone (20 mg oxycodone HCl Teva, oral immediate release), or one of the three other drugs not discussed in this publication.

Techniques:

Pharmacokinetic data from 12 subjects taking 20 mg oral oxycodone. Graph shows average drug concentrations in time. Error bars represent standard deviations. Peak drug concentration was observed at 1 h after intake.

Journal: Sensors (Basel, Switzerland)

Article Title: Opioid Detection Using Smartphone-Based Eye-Scanning

doi: 10.3390/s25175467

Figure Lengend Snippet: Pharmacokinetic data from 12 subjects taking 20 mg oral oxycodone. Graph shows average drug concentrations in time. Error bars represent standard deviations. Peak drug concentration was observed at 1 h after intake.

Article Snippet: Thereafter, participants were administered the medicinal product: oxycodone (20 mg oxycodone HCl Teva, oral immediate release), or one of the three other drugs not discussed in this publication.

Techniques: Concentration Assay

Correlation between light intensity and pupil size for different study conditions. Effect of oxycodone intake on pupil size in correlation to the amount of light in the room; home measurements separated from the measurements made during the study visits. This shows that after oxycodone intake, the pupil size is reduced (in both dark- and bright-light settings).

Journal: Sensors (Basel, Switzerland)

Article Title: Opioid Detection Using Smartphone-Based Eye-Scanning

doi: 10.3390/s25175467

Figure Lengend Snippet: Correlation between light intensity and pupil size for different study conditions. Effect of oxycodone intake on pupil size in correlation to the amount of light in the room; home measurements separated from the measurements made during the study visits. This shows that after oxycodone intake, the pupil size is reduced (in both dark- and bright-light settings).

Article Snippet: Thereafter, participants were administered the medicinal product: oxycodone (20 mg oxycodone HCl Teva, oral immediate release), or one of the three other drugs not discussed in this publication.

Techniques:

Dbase (z-pupil size) plotted vs. the log of ambient light measured with the mobile phone. Circles are before and triangles after administration of oxycodone. The classification results from a simple model with Dbase (z-pupil size) and Log light are shown in color. Black triangles are true positives and green triangles false negatives. Blue circles are true negatives and red circles false positives.

Journal: Sensors (Basel, Switzerland)

Article Title: Opioid Detection Using Smartphone-Based Eye-Scanning

doi: 10.3390/s25175467

Figure Lengend Snippet: Dbase (z-pupil size) plotted vs. the log of ambient light measured with the mobile phone. Circles are before and triangles after administration of oxycodone. The classification results from a simple model with Dbase (z-pupil size) and Log light are shown in color. Black triangles are true positives and green triangles false negatives. Blue circles are true negatives and red circles false positives.

Article Snippet: Thereafter, participants were administered the medicinal product: oxycodone (20 mg oxycodone HCl Teva, oral immediate release), or one of the three other drugs not discussed in this publication.

Techniques:

Z-pupil size (y-axis) versus log10 (ambient light) for ten individuals without corneal arcus, including data from home, sober at study site and under the influence of oxycodone at study site.

Journal: Sensors (Basel, Switzerland)

Article Title: Opioid Detection Using Smartphone-Based Eye-Scanning

doi: 10.3390/s25175467

Figure Lengend Snippet: Z-pupil size (y-axis) versus log10 (ambient light) for ten individuals without corneal arcus, including data from home, sober at study site and under the influence of oxycodone at study site.

Article Snippet: Thereafter, participants were administered the medicinal product: oxycodone (20 mg oxycodone HCl Teva, oral immediate release), or one of the three other drugs not discussed in this publication.

Techniques:

Z-pupil size (y-axis) versus log10 (ambient light) for two individuals with corneal arcus, including data from home, sober at study site and under the influence of oxycodone at study site.

Journal: Sensors (Basel, Switzerland)

Article Title: Opioid Detection Using Smartphone-Based Eye-Scanning

doi: 10.3390/s25175467

Figure Lengend Snippet: Z-pupil size (y-axis) versus log10 (ambient light) for two individuals with corneal arcus, including data from home, sober at study site and under the influence of oxycodone at study site.

Article Snippet: Thereafter, participants were administered the medicinal product: oxycodone (20 mg oxycodone HCl Teva, oral immediate release), or one of the three other drugs not discussed in this publication.

Techniques:

Open drug intervention clinical trials in clinicaltrials.gov that include “circadian,” “clock,” or “chronobiology” as a keyword .

Journal: Frontiers in Pharmacology

Article Title: Personalized medicine for pathological circadian dysfunctions

doi: 10.3389/fphar.2015.00125

Figure Lengend Snippet: Open drug intervention clinical trials in clinicaltrials.gov that include “circadian,” “clock,” or “chronobiology” as a keyword .

Article Snippet: Mundipharma Research GmbH & Co KG , Drug: Oxycodone/Naloxone prolonged release (OXN PR) tablets; oxycodone prolonged release (OxyPR) tablets , Pain|Constipation , Phase 3 , NCT01438567.

Techniques: Clinical Proteomics, Biomarker Discovery, Modification, Saline, Control, Capsules, Blocking Assay

Anti-counterfeit technologies used in brand pharmaceutical products [ <xref ref-type= 39 , 40 ]" width="100%" height="100%">

Journal: Scientia Pharmaceutica

Article Title: Anti-Counterfeit Technologies: A Pharmaceutical Industry Perspective

doi: 10.3797/scipharm.1202-03

Figure Lengend Snippet: Anti-counterfeit technologies used in brand pharmaceutical products [ 39 , 40 ]

Article Snippet: Purdue pharma L.P. , Oxycontin , Oxycodone HCl , RFID.

Techniques:

Rescue  oxycodone  use (mg)

Journal: Journal of Pain Research

Article Title: Postoperative pain management with transdermal fentanyl after forefoot surgery: a randomized, placebo-controlled study

doi: 10.2147/JPR.S69511

Figure Lengend Snippet: Rescue oxycodone use (mg)

Article Snippet: When discharged, the patients received two 10 mg slow-release oxycodone tablets (OxyContin ® , Mundipharma) to be used as rescue medication.

Techniques: